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在执行USP-NF方法时,若需做红外鉴别,需用样品的红外图谱与USP的红外标准图谱集进行比较,这种说法正确吗?

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加菲 二阶会员 用户来自于: 广东省广州市
2020-04-06 12:44

此说法是错误的。根据通则“<197> SPECTROPHOTOMETRIC IDENTIFICATION TESTS”规定:

"Record the spectra of the test specimen and the corresponding USP Reference Standard over the range from about 2.6 µm to 15 µm (3800 cm–1 to 650 cm–1) unless otherwise specified in the individual monograph.The IR absorption spectrum of the preparation of the test specimen, previously dried under conditions specified for the corresponding Reference Standard unless otherwise specified, or unless the Reference Standard is to be used without drying, exhibits maxima only at the same wavelengths as that of a similar preparation of the corresponding USP Reference Standard......"

     


 另外,在通则"<851> SPECTROPHOTOMETRY AND LIGHT-SCATTERING"中对于USP标准品用于药典分光光度法测试也有相应规定和描述。

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发布时间
2020-04-06 12:43
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2020-04-06 12:44
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