1 回答
It is recommended to submit the extraction study report forthe product under application, clarifying the extraction method and the basis for determining the extraction limit. If the extraction studyreport of products of the same kind or similar products is submittedas the basis for such determination, it is recommended to selectproducts with similar formulation, e.g., those only with differences incontent of color additives. It is not recommended to select productswith significant differences with the product under application informulation.It is also recommended to describe the similaritiesand differences between the selected products and the productunder application and demonstrate that such selected productsare representative, which can be discussed from raw materialformulation, dry weight of both products, recommended wearingperiod, etc., and analyze whether the differences affect the results ofextraction study. Attention should be given to the rationality of theupper limit of extraction rate.